[1] UCCELLI A, MORETTA L, PISTOIA V.Mesenchymal stem cells in health and disease[J]. Nat Rev Immunol, 2008, 8(9): 726
[2] 李佳潞,何斌,汤红明,等.全球干细胞临床研究现状与展望[J].海南医学,2024,35(7): 1044
LI JL, HE B, TANG HM, et al.Current status and prospects of global stem cell clinical research[J]. Hainan Med J, 2024, 35(7): 1044
[3] TOKUNAGA K, SAITOH N, GOLDBERG IG, et al.Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells[J]. Sci Rep, 2014, 4(1): 6996
[4] HEBERT PDN, CYWINSKA A, BALL SL, et al.Biological identifications through DNA barcodes[J]. Proc Biol Sci, 2003, 270(1512): 313
[5] MORALLI D, YUSUF M, MANDEGAR MA, et al.An improved technique for chromosomal analysis of human ES and iPS cells[J]. Stem Cell Rev Rep, 2010, 7(2): 471
[6] SEO JH, CHO SR.Neurorestoration induced by mesenchymal stem cells: potential therapeutic mechanisms for clinical trials[J]. Yonsei Med J, 2012, 53(6): 1059
[7] CALLONI R, CORDERO EAA, HENRIQUES JAP, et al.Reviewing and updating the major molecular markers for stem cells[J]. Stem Cells Dev, 2013, 22(9): 1455
[8] ZHAO W, JI X, ZHANG F, et al.Embryonic stem cell markers[J]. Molecules, 2012, 17(6): 6196
[9] PRIPUZOVA NS, GETIE-KEBTIE M, GRUNSEICH C, et al.Development of a protein marker panel for characterization of human induced pluripotent stem cells (hiPSCs) using global quantitative proteome analysis[J]. Stem Cell Res, 2015, 14(3): 323
[10] SHEKARI F, NEZARI H, LARIJANI MR, et al.Proteome analysis of human embryonic stem cells organelles[J]. J Proteomics, 2017, 162: 108
[11] HOFSTEEN P, ROBITAILLE AM, CHAPMAN DP, et al.Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling[J]. Proc Natl Acad Sci U S A, 2016, 113(4): 1002
[12] MEYFOUR A, PAHLAVAN S, MIRZAEI M, et al.The quest of cell surface markers for stem cell therapy[J]. Cell Mol Life Sci, 2020, 78(2): 469
[13] ONIONS D, KOLMAN J.Massively parallel sequencing, a new method for detecting adventitious agents[J]. Biologicals, 2010, 38(3): 377
[14] 干细胞制剂质量控制及临床前研究指导原则(试行)[S]. 2015
Guiding Principles for Quality Control and Preclinical Study of Stem Cell Preparations (Trial)[S]. 2015
[15] ZHUANG WZ, LIN YH, SU LJ, et al.Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications[J]. J Biomed Sci, 2021, 28(1): 28
[16] KIDD S, SPAETH E, DEMBINSKI JL, et al.Direct evidence of mesenchymal stem cell tropism for tumor and wounding microenvironments using in vivo bioluminescent imaging[J]. Stem Cells, 2009, 27(10): 2614
[17] CRIPPA S, BERNARDO ME.Mesenchymal stromal cells: role in the BM niche and in the support of hematopoietic stem cell transplantation[J]. Hemasphere, 2018, 2(6): e151
[18] ATIYA H, FRISBIE L, PRESSIMONE C, et al.Mesenchymal stem cells in the tumor microenvironment[J]. Adv Exp Med Biol, 2020, 12(34): 31
[19] FRISBIE L, BUCKANOVICH RJ, COFFMAN L.Carcinoma-associated mesenchymal stem/stromal cells: architects of the pro-tumorigenic tumor microenvironment[J]. Stem Cells, 2022, 40(8): 705
[20] 临床研究用人脐带来源间充质干细胞制剂规范[S]. 2018: 1
Product Specification of Human Umbilical Cord Derived Mesenchymal Stem Cell for Clinical Research[S]. 2018: 1
[21] 韩晓燕,纳涛,张可华,等.人间充质干细胞生物学有效性的质量评价[J].中国新药杂志,2018,27(21): 2511
HAN XY, NA T, ZHANG KH, et al.Quality evaluation for biological effectiveness of human mesenchymal stem cells[J]. Chin J New Drugs, 2018, 27(21): 2511
[22] 张郭,汪振星,孙家明. 人脂肪来源干细胞的免疫调控及其临床应用[J]. 现代免疫学,2022,42(5): 427
ZHANG G, WANG ZX, SUN JM.Immunomodulation and clinical applications of human adipose-derived stem cells[J]. Curr Immunol, 2022, 42(5): 427
[23] MUNIR H, MCGETTRICK HM.Mesenchymal stem cell therapy for autoimmune disease: risks and rewards[J]. Stem Cells Dev, 2015, 24(18): 2091
[24] WEISS ARR, DAHLKE MH.Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs[J]. Front Immunol, 2019, 10: 1191
[25] MELIEF SM, GEUTSKENS SB, FIBBE WE, et al.Multipotent stromal cells skew monocytes towards an anti-inflammatory interleukin-10-producing phenotype by production of interleukin-6[J]. Haematologica, 2013, 98(6): 888
[26] KIM JH, JO CH, KIM HR, et al.Comparison of immunological characteristics of mesenchymal stem cells from the periodontal ligament, umbilical cord, and adipose tissue[J]. Stem Cells Int, 2018, 2018: 8429042
[27] SONG N, SCHOLTEMEIJER M, SHAH K.Mesenchymal stem cell immunomodulation: mechanisms and therapeutic potential[J]. Trends Pharmacol Sci, 2020, 41(9): 653
[28] 符禹玄,陈君,赵富生,等. NRG1基因修饰的骨髓基质横切损伤的修复作用及其机制[J]. 解放军医学杂志,2024,49(2): 204
FU YX, CHEN J, ZHAO FS, et al.Effect and mechanism of transplantation bone marrow stromal stem cells transfected NRG1 gene on repair of hemi-transected spinal cord injury in rats[J]. Med J Chin PLA, 2024, 49(2): 204
[29] 张晨亮,李欣,米一,等. 基因修饰间充质干细胞治疗肿瘤研究进展[J]. 药物评价研究,2021,44(10): 2049
ZHANG CL, LI X, MI Y, et al.Research progress of genetically modified mesenchymal stem cells in treatment of tumors[J]. Drug Eval Res, 2021, 44(10): 2049
[30] European Medicines Agency. Quality, Non-clinical and Clinical Aspects of Medicinal Products Containing Genetically Modified Cells[EB/OL]. (2021-06-01)[2025-01-08]. https://www.ema.europa.eu/en/quality-non-clinical-clinical-aspects-medicinal-products-containing-genetically-modified-cells-scientific-guideline
[31] 纳涛,王磊,郝捷,等. 人胚胎干细胞来源的视网膜色素上皮细胞质量控制研究[J]. 生命科学,2018,30(3): 248
NA T, WANG L, HAO J, et al.The quality control studies on human embryonic stem cells-derived retinal pigment epithelial cells[J]. Chin Bull Life Sci, 2018, 30(3): 248
[32] 王聪,周建政. 间充质干细胞来源的外泌体治疗早发性卵巢功能不全的研究进展[J]. 中国性科学,2024,33(7): 35
WANG C, ZHOU JZ.Research progress of exosomes derived from mesenchymal stem cells in treatment of premature ovarian insufficiency[J]. Chin J Hum Sexual, 2024, 33(7): 35
[33] LOTFY A, ABOQUELLA NM, WANG H.Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials[J]. Stem Cell Res Ther, 2023, 14(1): 66
[34] BÖRGER V, BREMER M, FERRER-TUR R, et al. Mesenchymal stem/stromal cell-derived extracellular vesicles and their potential as novel immunomodulatory therapeutic agents[J]. Int J Mol Sci, 2017, 18(7): 1450
[35] LIEW LC, KATSUDA T, GAILHOUSTE L, et al.Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer’s disease[J]. Int Immunol, 2017, 29(1): 11
[36] WANG R, XU B.TGFβ1-modified MSC-derived exosome attenuates osteoarthritis by inhibiting PDGF-BB secretion and H-type vessel activity in the subchondral bone[J]. Acta Histochem, 2022, 124(7): 151933