Combination of enzymatic digestion-mass spectrometry and cyanylation cleavage to analyze disulfide bonds of new drug recombinant human insulin aspart

HUANG Ya-juan1,2, FU Hai-yuan2, HOU Li-ping1,2, SUN Yun-bo2, ZHANG Tuo2, WANG Dong-mao2, ZHENG Jun-jie2, WEI Kai-hua2

Chinese Journal of Pharmaceutical Analysis ›› 2013, Vol. 33 ›› Issue (10) : 1649-1655.

Chinese Journal of Pharmaceutical Analysis ›› 2013, Vol. 33 ›› Issue (10) : 1649-1655.

Combination of enzymatic digestion-mass spectrometry and cyanylation cleavage to analyze disulfide bonds of new drug recombinant human insulin aspart

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