Objective: To explore the definition and systematic taxonomy of bioassay method, to provide ideas for better understanding the essence of bioassay. Methods: According to the attribute characteristics of bioassay, the classification framework of bioassay was established and the meaning for the classification was explained. Results: (1) The definition of bioassay has different emphases, mainly due to the different focus in various fields, but the theme was basically the same. (2)Potency and its derivative terms had their definitive connotations and extents in bioassay, and accurate use of these terms could make the expression more professional and clearer. (3) Bioassays could be classified according to many attributes, such as whether directness or not of the biological effect detected, the type of the biological subsector used for assay, the nature and mechanism of the bioassay, and the data type of reportable value of the bioassay. Conclusion: Accurate and standardized definition and classification of bioassay are not only conducive to the standardization of expression for use, but also provide theoretical basis and technical support for further understanding, application and improvement of bioassay.
LI Na, DU Ying, LIU Cui, ZHENG Xue-xue, LI Xiang-qun, TAN De-jiang
. Definition and taxonomy of biological method*[J]. Chinese Journal of Pharmaceutical Analysis, 2022
, 42(6)
: 931
-936
.
DOI: 10.16155/j.0254-1793.2022.06.02
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