Safety Monitoring

Analysis of extracts from pharmaceutical glass vials*

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  • Shanghai Food And Drug Packaging Material Control Center, Shanghai 201203, China

Received date: 2023-02-12

  Online published: 2024-06-24

Abstract

Objective: To study the extracts of pharmaceutical glass vails and conduct differential analysis on the extracted elements. Methods: A method for the determination of 17 elements in glass vials under different erosion medium by inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS) was established. The determination of extracts in different medium of glass vails was carried out. Results: The difference in extraction medium, glass vials manufacturer, production process, glass type, etc. has a significant impact on the measurement results. Conclusion: It is necessary to pay attention to the impact of different types of drugs, different manufacturers, different production processes, and different glass types on the quality and safety of injections.

Cite this article

ZHANG Fang-fang, ZHANG Feng-lan, HUO Jing-yi . Analysis of extracts from pharmaceutical glass vials*[J]. Chinese Journal of Pharmaceutical Analysis, 2023 , 43(9) : 1494 -1499 . DOI: 10.16155/j.0254-1793.2023.09.06

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