Objective: To study the extracts of pharmaceutical glass vails and conduct differential analysis on the extracted elements. Methods: A method for the determination of 17 elements in glass vials under different erosion medium by inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS) was established. The determination of extracts in different medium of glass vails was carried out. Results: The difference in extraction medium, glass vials manufacturer, production process, glass type, etc. has a significant impact on the measurement results. Conclusion: It is necessary to pay attention to the impact of different types of drugs, different manufacturers, different production processes, and different glass types on the quality and safety of injections.
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