Review & Monography

Preparation method of bioaffinity chromatography and its application progress in the research of effective substances in traditional Chinese medicine*

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  • 1. School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou 311400, China;
    2. Department of Medicine, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou 310007, China

Received date: 2023-06-06

  Online published: 2024-06-24

Abstract

Bioaffinity chromatography is a chromatographic method that identifies the bioactive components via specific binding affinity between the analytes and chromatographic stationary phase. It has high sensitivity and high selectivity. This article mainly reviewed the preparation and applications of immunoaffinity chromatography, lectin affinity chromatography, cell membrane chromatography and immobilized metal affinity chromatography. Moreover, the prospects of these affinity chromatographic methods were also discussed.

Cite this article

YE Qi-tao, DENG Xue-hui, XU Ping-cui, LIN Bing-feng, SHOU Dan, WANG Na-ni . Preparation method of bioaffinity chromatography and its application progress in the research of effective substances in traditional Chinese medicine*[J]. Chinese Journal of Pharmaceutical Analysis, 2023 , 43(7) : 1091 -1103 . DOI: 10.16155/j.0254-1793.2023.07.01

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