Review & Monography

Progress of analytical methods of cardiac glycosides in biological samples*

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  • 1. People’s Public Security University of China, Beijing 100038, China;
    2. Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China

Received date: 2022-07-09

  Online published: 2024-06-25

Abstract

The detection of cardiac glycosides in biological samples requires efficient extraction methods and high-sensitivity analytical methods. Among them, laboratory tests include protein precipitation, solid-phase extraction, solid-phase support-liquid-liquid extraction, liquid-liquid microextraction, QuEChERS and other sample pretreatment technologies, as well as liquid chromatography-mass spectrometry, real-time direct analysis-mass spectrometry, capillary electrophoresis and other analytical methods. Field rapid detection includes immunoassay, biosensor etc. Finally, this review makes a preliminary discussion on the shortcomings and development prospects of the current cardiac glycosides analysis and sample pretreatment methods. This review provides references for the detection of cardiac glycosides in forensic science and clinical treatment.

Cite this article

SUN Yi-jian, CHANG Jing, ZOU Bo, WANG Ji-fen, WANG Ai-hua, LI Jia-yi . Progress of analytical methods of cardiac glycosides in biological samples*[J]. Chinese Journal of Pharmaceutical Analysis, 2023 , 43(5) : 721 -730 . DOI: 10.16155/j.0254-1793.2023.05.01

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