Review & Monography

Applications of solid phase microextraction coupled to ambient ionization mass spectrometry in the analyzation of harmful drugs in food*

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  • Comprehensive Technical Service Center of Weifang Customs, Weifang 261041, China

Received date: 2021-05-25

  Online published: 2024-06-26

Abstract

Harmful drug residues in food are related to everyone’s health and are a major challenge for food safety practitioners. Developing a fast, efficient, and "green" analytical method is the primary goal of technicians in food analysis. Compared to the QuEChERS method, which is the most used methodology for food sample preparation, SPME technology may have more advantages (e.g., automation, solvent-free, and sample miniaturization). SPME coupled to ambient ionization mass spectrometry (AIMS) will generate new technology, so-called SPME-AIMS. SPME-AIMS is suitable for on-site inspection of the actual sample, and can reduce the total sample analysis time down to 10 s. Rely on its "green" performance, SPME-AIMS might replace the traditional method in the future. This review will discuss the latest developments in the field of food analysis by means of SPME-AIMS. Hopefully, providing new ideas for scientists in this area.

Cite this article

GONG Xiao-ming, LI Kai, HUA Meng-meng, KONG Cai-xia, XU Wen-juan, LIU Wen-peng, TIAN Guo-ning . Applications of solid phase microextraction coupled to ambient ionization mass spectrometry in the analyzation of harmful drugs in food*[J]. Chinese Journal of Pharmaceutical Analysis, 2022 , 42(3) : 370 -379 . DOI: 10.16155/j.0254-1793.2022.03.02

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