Objective: To compare the mechanical properties of allogenic dermal patch and bovine pericardial patch under the same manufacturing process,so as to provide reference for product development and clinical use in related industries. Methods: The tensile strength,elongation at break and suture strength of bovine pericardial patches made by manufacturers A and B and allogenic dermal patches made by manufacturers C and D were tested and statistically analyzed. Results: There was no significant difference in tensile strength,elongation at break and suture strength between bovine pericardial patches from manufacturers A and B（P>0.05）. The average values of samples were 23.18 MPa,32.84% and 11.46 N,and the standard deviations were 2.85,5.08 and 1.46,respectively. There was no significant difference in tensile strength,elongation at break and suture strength between allogeneic dermal patches from manufacturers C and D（P>0.05）. The average values of samples were 8.91 MPa,65.64% and 22.71 N,and the standard deviations were 0.77,4.84 and 2.78,respectively. There was significant difference in mechanical properties between bovine pericardial patch and allogeneic dermal patch（P<0.01）. Conclusion: The experimental results showed that bovine pericardial patch has better tensile strength compared to allogenic dermal patch. While allogenic dermal patch perform better in elongation at break and suture strength.
LI Chong-chong, HAN Qian-qian, LIU Li, WANG Chun-ren
. Study on the mechanical properties of two types of biological patches*[J]. Chinese Journal of Pharmaceutical Analysis, 2021
, 41(6)
: 1041
-1045
.
DOI: 10.16155/j.0254-1793.2021.06.15
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