Ingredient Analysis

Study on the volatile components of Epimedium extract and its pyrolysis products*

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  • 1. School of Third Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, China;
    2. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China;
    3. China Tobacco Jiangsu Industrial Co., Ltd., Nanjing 210019, China

Received date: 2024-03-02

  Online published: 2024-10-17

Abstract

Objective: To investigate the flavor components of Epimedium extract and analyze pyrolysis products of the extracts from Epimedium. Methods: Ultra fast gas phase electronic nose was adopted to analyze volatile components in ethanol extracts of Epimedium and the alcohol extracting process of Epimedium was optimized by orthogonal experiment. Epimedium extract was pyrolysed to simulate cigarette smoking by TG-GC-MS. The lysates of Epimedium extract were analysed in a nitrogen environment, and the possible lysate mechanism of the products was reasonably speculated. Results: 22 volatile components were detected in the ethanol extracts of Epimedium at different concentrations. Concentration of Epimedium extracted with 60% ethanol was superior than others. Analyzing pyrolysis products of Epimedium extract, 78 compounds were identified at 150, 300 and 450 ℃, including aldehydes, ketones, alcohols, phenols, furans and benzene series. Conclusion: Ethanol extraction of Epimedium contains many aromatic volatile components. A large number of ketones, alcohols, phenols, furans and other volatile aroma compounds are produced after pyrolysis of Epimedium extract.

Cite this article

LIU Ling-run, TIAN Shi-ling, WU Chang-jian, CHEN Rui, YE Yuan-qing, QIN Yan-hua, YIN Zhi-qi, CAO Yi, ZHANG Jian . Study on the volatile components of Epimedium extract and its pyrolysis products*[J]. Chinese Journal of Pharmaceutical Analysis, 2024 , 44(9) : 1485 -1496 . DOI: 10.16155/j.0254-1793.2024-0136

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