[1] 马生军, 刘建慧, 马留纯, 等. 不同产地及生长年限曼地亚红豆杉中10-脱乙酰基巴卡亭Ⅲ、三尖杉宁碱、紫杉醇量的比较分析[J]. 中草药, 2017, 48(23): 4979
MA SJ, LIU JH, MA LC, et al. Comparative analysis on contents of 10-deacetyl-bacratin Ⅲ, cephalomannine, taxol of Taxus media from different habitats and growth years[J]. Chin Tradit Herb Drugs, 2017, 48(23): 4979
[2] 吴长桥, 蒋路园, 杨艳芳, 等. 红豆杉属植物中紫杉烷化合物含量比较与分析[J]. 中草药, 2021, 52(2): 538
WU CQ, JIANG LY, YANG YF, et al. Comparison and analysis of taxane compounds in Taxus[J]. Chin Tradit Herb Drugs, 2021, 52(2): 538
[3] 刘向前, 张晓丹, 朱育林, 等. 曼地亚红豆杉双黄酮结构表征和Taxol定量[J]. 中药材, 2008, 31(10): 1498
LIU XQ, ZHANG XD, ZHU YL, et al. Structure identification of biflavones and determination of taxol from Taxus media[J]. J Chin Med Mater, 2008, 31(10): 1498
[4] 徐蕊, 吴泰宗, 范杰平. 曼地亚红豆杉枝叶挥发油化学成分的GC-MS分析[J]. 南昌大学学报(工科版), 2013, 35(1): 22
XU R, WU TZ, FAN JP. GC-MS analysis of the chemical constituents of the essential oil from Taxus media by different extraction methods[J]. J Nanchang Univ(Eng Technol), 2013, 35(1): 22
[5] 李振麟, 吕旭辉, 王新婕, 等. 曼地亚红豆杉枝叶化学成分研究[J]. 中草药, 2018, 49(14): 3226
LI ZL, LÜ XH, WANG XJ, et al. Chemical constituents from twig and leaves of Taxus media[J]. Chin Tradit Herb Drugs, 2018, 49(14): 3226
[6] 戴淑颖, 张郜晨茜, 刘怿, 等. 南方红豆杉水提物通过激活自噬下调PD-L1增强IFN-γ抗肿瘤作用的体外研究[J]. 中华中医药杂志, 2022, 37(9): 5114
DAI SY, ZHANG GCQ,LIU Y, et al. Study on the antitumor effect of IFN-γ in vitro promoting by aqueous extract of Taxus mairei (Lemee et Levl.) S. Y. Hu ex Liu via the modulation autophagy and down-regulating PD-L1 expression[J]. China J Tradit Chin Med Pharm, 2022, 37(9): 5114
[7] 汤彬. 南方红豆杉枝叶降血糖的物质基础研究[D]. 南京: 南京中医药大学, 2014
TANG B. Study on Material Basis of Hypoglycemic Effect of Taxus chinensis Branches and Leaves[D]. Nangjing: Nanjing University of Chinese Medicine, 2014
[8] 徐迪, 苏超, 张洋. 曼地亚红豆杉精油组分及其抑菌活性研究[J]. 绵阳师范学院学报, 2021, 40(5): 75
XU D, SU C, ZHANG Y. Study on components and antibacterial activity of essential oil from Taxus media[J]. J Mianyang Norm Univ, 2021, 40(5): 75
[9] 吕旭辉. 曼地亚红豆杉和亮叶杨桐化学成分研究[D]. 南京: 南京中医药大学, 2018
LÜ XH. Study on the Chemical Constituents of Taxus media and Adinandra nitida[D]. Nangjing: Nanjing University of Chinese Medicine, 2018
[10] 王希清, 寇萍, 李弘琨, 等. 红豆杉资源加工利用产业发展现状[J]. 生物质化学工程, 2020, 54(6): 13
WANG XQ, KOU P, LI HK, et al. Industrialization development status of Taxus resources[J]. Biomass Chem Eng, 2020, 54(6): 13
[11] 薛雪, 朱龙平, 杨得坡, 等. 红豆杉活性成分筛选的一种新方法的研究[J]. 药物分析杂志, 2020, 40(7):1178
XU X, ZHU LP, YANG DP, et al. New screening method for active constituents in Taxus chinensis[J]. Chin J Pharm Anal, 2020, 40(7):1178
[12] 王亚坤, 裴静波, 谢长生,等. 南方红豆杉水提物对HER2阳性人NCI-N87胃癌移植瘤生长及凋亡作用[J]. 中华中医药学刊, 2016, 34(8): 1949
WANG YK, PEI JB, XIE CS, et al. Taxus chinensis var mairei (AETC) inhibiting HER2 positive human gastric cancer cells NCI-N87 transplantation tumor and inducing apoptosis[J]. Chin Arch Tradit Chin Med, 2016, 34(8): 1949
[13] 黑龙江省中药材标准 2001年版[S]. 2001: 232
Heilongjiang Provincial Standard for Traditional Chinese Medicine Materials 2001[S]. 2001: 232
[14] 中华人民共和国卫生部药品标准 维吾尔族药分册[S]. 1999: 32
The Fascicle of Uyghur Medicine of Drug Standard of Ministry of Public Health of the People’s Republic of China[S]. 1999: 32
[15] 浙江省中药材标准. 第一册[S]. 2016: 24
Zhejiang Provincial Standard for Traditional Chinese Medicine Materials. VolⅠ[S]. 2016: 24
[16] 广东省中药材标准. 第一册[S]. 2018: 346
Guodong Provincial Standard for Traditional Chinese Medicine Materials. VolⅠ[S]. 2018: 346
[17] 湖北省中药材标准 2018年版[S]. 2018: 161
Hubei Provincial Standard for Traditional Chinese Medicine Materials 2018[S]. 2018:161
[18] 陈莉, 王盛, 刘柳珊, 等. 基于质量标志物有效性、特有性及可测性理念的天葵子Q-marker成分预测[J]. 药物分析杂志, 2023, 43(10):1672
CHEN L, WANG S, LIU LS, et al. Q-marker component prediction of Semiaquilegiae Radix based on the concept of effectiveness, specificity and testability of quality markers[J]. Chin J Pharm Anal, 2023, 43(10):1672
[19] 张铁军, 白钢, 刘昌孝. 中药质量标志物的概念、核心理论与研究方法[J]. 药学学报, 2019, 54(2): 187
ZHANG TJ, BAI G, LIU CX. The concept, core theory and research methods of Chinese medicine quality markers[J]. Acta Pharm Sin, 2019, 54(2):187
[20] 童欢, 张明伟, 张炳武, 等. 基于指纹图谱、含量测定和化学模式识别的五子衍宗丸质量评价研究[J]. 药物分析杂志, 2023, 43(1):103
TONG H, ZHANG MW, ZHANG BW, et al. Study on quality evaluation of Wuziyanzong pills based on HPLC fingerprint, assay and chemical pattern recognition[J]. Chin J Pharm Anal, 2023,43(1):103
[21] 朱雪亚, 李泽运, 张潇, 等. 清热解毒口服液中6个药物成分的定量分析与网络药理学研究[J]. 药物分析杂志, 2022, 42(9):1537
ZHU XY, LI ZY, ZHANG X, et al. Quantitative analysis and network pharmacology research based on 6 components in Qingre Jiedu oral liquid[J]. Chin J Pharm Anal, 2022, 42(9):1537
[22] 匡雪君, 王彩霞, 邹丽秋, 等. 紫杉醇生物合成途径及合成生物学研究进展[J]. 中国中药杂志, 2016, 41(22): 4144
KUANG XJ, WANG CX, ZHOU LQ, et al. Recent advances in biosynthetic pathway and synthetic biology of taxol[J]. China J Chin Mater Med, 2016, 41(22): 4144
[23] 卫强, 孙涛. 红豆杉的抗肿瘤活性成分及其衍生物研究进展[J]. 天然产物研究与开发, 2016, 28(10): 1664
WEI Q, SUN T. Review on anti-tumor components from Taxus and their derivatives[J]. Nat Prod Res Dev, 2016, 28(10): 1664
[24] 张应龙, 刘维, 江洪. 紫杉醇对鼻咽癌细胞株CNE2的增殖抑制作用及对PI3K/AKT/p53信号通路的影响[J]. 中国临床药理学杂志, 2018, 34(14): 1652
ZHANG YL, LIU W, JIANG H. Effect of paclitaxel on proliferation inhibitory of nasopharyngeal carcinoma cell line CNE2 and its intervention on PI3K/AKT/p53 signal pathway[J]. Chin J Chin Pharmacol, 2018, 34(14): 1652
[25] 陶红芳, 方建林, 刘元生, 等. 紫杉醇下调死亡结构域沉默子表达促进白血病细胞凋亡新机制研究[J]. 中华实用儿科临床杂志, 2014, 29(11): 862
TAO HF, FANG JL, LIU YS, et al. Increase of leukemia cell apoptosis through the down-regulation of silencer of death domains by paclitaxel[J]. Chin J Appl Clin Pediatr, 2014, 29(11): 862
[26] 冯锦, 吴建红, 熊响莲, 等. 紫杉醇通过调控JAK2/STAT3通路对肝纤维化模型大鼠Th17/Treg影响的研究[J]. 中国免疫学杂志, 2022, 38(13): 1564
FENG J, WU JH, XIONG XL, et al. Paclitaxel regulates effect of JAK2/STAT3 pathway on Th17/Treg in hepatic fibrosis model rats[J]. Chin J Immunol, 2022, 38(13): 1564
[27] 向雷, 黄智, 张帅, 等. 磷脂酰肌醇3激酶调节亚基1过表达对肝细胞癌进展的影响[J]. 介入放射学杂志, 2019, 28(10): 962
XIANG L, HUANG Z, ZHANG S, et al. The effect of overexpression of PIK3R1 on the progression of hepatocellular carcinoma[J]. J Interv Radiol, 2019, 28(10): 962
[28] ANDRADE VP, MORROGH M, QIN LX, et al. Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion[J]. Mol Oncol, 2015, 9(4): 772
[29] WONG H, LEVENGA J, LAPLANTE L, et al. Akt inaffective behavior, spatial memory, and extinction related to psychiatric disorders[J]. Elife, 2020, 16(9): e56630
[30] RAI SN, DILNASHIN H, et al. The role of P13K/Akt and ERK in neurodegenerative disorders[J]. Neurotox Res, 2019, 35(3): 775
[31] MACK PC, BANKS KC, ESPENSCHIED CR, et al. Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung-cancer: analysis of over 8000 cases[J]. Cancer, 2020, 126(14): 3219
[32] CHEN SJ, LI FY, XU D, et al. The function of RAS mutationin cancer and advance sinits drug research[J]. Curr Pharm Design, 2019, 25(10): 1105
[33] 张倩楠, 贾琴琴, 杨婷婷, 等. MAPK1基因沉默对肺癌A549细胞增殖、凋亡、迁移和侵袭能力的影响[J]. 宁夏医科大学学报, 2022, 44(4): 373
ZHANG QN, JIA QQ, YANG TT, et al. Effect of MAPK1 gene silencing on proliferation, apoptosis, migration and invasion of lung cancer A549 cells[J]. J Ningxia Med Univ, 2022, 44(4): 373
[34] 王信, 李莉, 张瑞, 等. 基于指纹图谱和网络药理学的白花蛇舌草质量标志物预测分析[J]. 中国医院药学杂志, 2022, 42(16): 1633
WANG X, LI L, ZHANG R, et al. Predictive analysis of quality markers of Oldenlandia diffusa (Willd.) Roxb based on fingerprint and network pharmacology[J]. Chin J Hosp Pharm, 2022, 42(16): 1633
[35] 白雪, 刘霞, 崔英, 等. 生长因子受体结合蛋白2rs238419遗传多态性与非小细胞肺癌患者铂类药物化疗疗效的相关性研究[J]. 中国临床药理学杂志, 2022, 38(20): 2387
BAI X, LIU X, CUI Y, et al. Correlation between genetic polymorphisms of growth factor receptor binding protein 2 and the efficacy of platinum-based chemotherapy in non-small cell lung cancer patients in Yanbian region[J]. Chin J Chin Pharmacol, 2022, 38(20): 2387
[36] 王雅楠, 马庆久, 徐建庆, 等. EphA2通过调控Grb2表达参与肝癌细胞侵袭的机制探讨[J]. 现代肿瘤医学, 2021, 29(1): 32
WANG YN, MA QJ, XU JQ, et al. The mechanisms of erythropoietin-producing hepatocellular A2 protein participating in the invasion of hepatocellular carcinoma cells via regulating the expression of growth factor receptor bound protein 2[J]. J Mod Oncol, 2021, 29(1): 32
[37] 史小娟, 徐志明, 付顺华, 等. 采收季节与年龄对曼地亚红豆杉主要活性成分的影响[J]. 中国中药杂志, 2010, 35(19): 2538
SHI XJ, XU ZM, FU SH, et al. Effects of gathering season and three age affect on main active components of Taxus media[J]. China J Chin Mater Med, 2010, 35(19): 2538
[38] 李时珍. 本草纲目[M]. 武汉: 崇文书局, 2008: 347
LI SZ. Compendium of Materia Medica[M]. Wuhan: Chongwen Publishing House, 2008: 347
[39] 叶觉诠. 本草推陈[M]. 南京: 江苏人民出版社, 1963: 247
YE JQ. Materia Medica Promoting Aging[M]. Nanjing: Jiangsu People’s Publishing House, 1963: 247
[40] 冯巍, 谈锋, 谢峻. 曼地亚红豆杉研究进展[J]. 中草药, 2007, 38(10): 1589
FENG W, TAN F, XIE J. Advances in studies on Taxus media[J]. Chin Tradit Herb Drugs, 2007, 38(10): 1589
[41] 景奉堂, 冯帅, 王静, 等. 基于指纹图谱和网络药理学的连翘质量标志物预测分析[J]. 中国药房, 2022, 33(3): 293
JING FT, FENG S, WANG J, et al. Predictive analysis of quality markers of Forsythia suspensa based on fingerprint and network pharmacology[J]. China Pharm, 2022, 33(3): 293
[42] 李健, 赖平安. 通过侧链结构修饰将三尖杉宁碱转化为紫杉醇的工艺研究[J]. 生物化工, 2020, 6(6): 15
LI J, LAI PA. Study on conversion of cephalomannine into paclitaxel by modification of side chain structure[J]. Biol Chem Eng, 2020, 6(6): 15
[43] 崔海超, 郑文艺, 张智慧, 等. 不同红豆杉属植物中7种紫杉烷类化合物的HPLC检测与分析[J]. 森林工程, 2022, 38(4): 118
CUI HC, ZHENG WY, ZHANG ZH, et al. Determination and analysis of seven taxanes in different Taxus species by HPLC method[J]. Forest Eng, 2022, 38(4): 118
[44] 王倩, 姜俊, 许霞, 等. 指纹图谱及网络药理学联合分析芪胶升白胶囊的药效成分及机制[J]. 中国中药杂志, 2023, 48(6): 1526
WANG Q, JIANG J, XU X, et al. Effective components and mechanism of Qijiao Shengbai capsules based on fingerprinting and network pharmacology[J]. China J Chin Mater Med, 2023, 48(6): 1526
[45] 黄露, 徐顶巧, 乐世俊, 等. 基于层次分析—熵权法和网络药理学的野马追质量标志物研究[J]. 中国中药杂志, 2021, 46(21): 5545
HUANG L, XU DQ, LE SJ, et al. Research on Q-markers of Eupatorium lindleyanum based on analytic hierarchy process-entropy weight method and network pharmacology[J]. China J Chin Mater Med, 2021, 46(21): 5545
[46] TANIGUCHI CM, WINNAY J, KONDO T, et al. The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling[J]. Cancer Res, 2010, 70(13): 5305
[47] 吴杰, 汤欢, 黄林芳, 等. 红豆杉属植物全球生态适宜性分析研究[J]. 药学学报, 2017, 52(7):1186
WU J, TANG H, HUANG LF, et al. Research and analysis of globally ecological suitability for Taxus plants[J]. Acta Pharm Sin, 2017, 52(7):1186
