Objective: To analyze the microstructure and contents of trace elements in mineral medicine realgar. Methods: Microscope and multi-receiver inductively coupled plasma mass spectrometry were used to test the microstructure and 42 kinds of trace elements in the mineral medicine realgar in Zhenfeng County and Ceheng County of Guizhou Province,and Excel and OriginPro 2016 software were used for statistical analysis of the data. Results: The realgar samples were veined, reticulated and lumped. Realgar has a relatively simple structure and is usually associated with minerals such as calcite. The content of Sb in realgar was higher than that of other elements, and the highest content was more than 2 000 μg·g-1. The contents of Ni, Zn, Gr and Sr were slightly lower and were generally about 10 μg·g-1. The contents of Li, Cr, Co, Cu, Sn, Ba and Pb were generally between 0.1-1 μg·g-1. The contents of other elements were very low and were less than 0.1 μg·g-1. Conclusion: The realgar mineral samples from Zhenfeng county and ceheng county of Guizhou Province are relatively simple in structure, high in crystallinity, high in purity, and low in trace element contents, which can be considered as mineral traditional Chinese medicine to use.
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