综述专论

新精神活性物质快速检测技术研究进展*

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  • 1.司法鉴定科学研究院上海法医学重点实验室上海市司法鉴定专业技术服务平台, 上海 200063;
    2.烟台大学, 烟台 264005
第一作者 Tel:(021)52352955;E-mail:18766560108@163.com
**Tel:(021)52352955;E-mail:chenh@ssfjd.cn

修回日期: 2022-01-09

  网络出版日期: 2024-06-26

基金资助

*十三五国家重点研发计划项目(2016YFC0800704);上海市科技攻关(19DZ120060);国家自然科学基金青年科学基金(81501633);上海市法医学重点实验室(17DZ2273200);上海市司法鉴定专业技术服务平台(19DZ2292700)

Research progress on rapid detectiontechniques of new psychoactive substances*

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  • 1. Department of Forensic Toxicology, Shanghai Key Laboratory Medicine, Shanghai Forensic Science Platform, Academy of Forensic Science, Shanghai 200063, China;
    2. School of Pharmacy, Yantai University, Yantai 264005, China

Revised date: 2022-01-09

  Online published: 2024-06-26

摘要

新精神活性物质分析是现阶段各国法医毒物学领域研究人员面临的焦点问题。为更有效遏制毒品滥用,打击毒品犯罪,需要各类技术的支撑,以面对新精神活性物质不断提出的挑战。精准、有效的快速检测技术不仅是对检材中是否含有新精神活性物质的有效初筛手段之一,个别快速检测技术还可以为新出现的新精神活性物质的早期预警提供技术支撑。本文主要围绕近年来报道的基于免疫、光谱和质谱原理的各种快速检测技术,对目前主流的新精神活性物质快速检测技术及其应用进行综述。

本文引用格式

周莉英, 向平, 陈航 . 新精神活性物质快速检测技术研究进展*[J]. 药物分析杂志, 2022 , 42(4) : 547 -556 . DOI: 10.16155/j.0254-1793.2022.04.01

Abstract

At this stage, new psychoactive substances(NPS) are the focus of researchers in the field of forensic toxicology in every country. In order to curb drug abuse and combat drug crimes more effectively, technical support for various analysis techniques is needed to face the challenges posed by NPS. Accurate and effective rapid detection techniques are not only one of the effective screening techniques for the presence of NPS in the samples,but also individual rapid detection techniques which can provide technical support for the emerging early warning of NPS. This article focuses on various rapid detection technologies based on the principles of immunity, spectroscopy, and mass spectrometry reported in recent years, and reviews the current mainstream rapid detection techniques for NPS and their applications.

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